Cell and gene therapies (CGTs) provide the opportunity to transform medicine across diverse disease areaswhere there is significant need for new treatment options. Valued at $15.46 billion in 2022, financial analystspredict the global cell and gene therapy market to grow to $82.24 billion by 2032. Some of the key driversfor this growth include a robust clinical pipeline, new regulatory approvals, the development of innovativetechnologies to improve production, and strategic collaborations between biotech companies and researchand manufacturing partners.1,2Currently, the clinical trials process for these advanced therapies is complex, involving multiple touchpoints,various providers and locations, and significant costs—all of which can negatively influence the patientexperience. Some of these challenges can be addressed through development and manufacturing strategiesand patient-centered trial design, which fall under the purview of partner Contract Development andManufacturing Organizations (CDMOs) and Contract Research Organizations (CROs). Integratingdevelopment, manufacturing, and clinical research services reduces the complexity of managing multiplevendors and ensures consistency and quality control throughout development and clinical trial management.It also facilitates more tailored solutions to meet specific trial needs, enhancing trial efficiency andcost-effectiveness. Ultimately, this cohesive approach not only simplifies logistical and operational aspectsbut also centers on the patient experience, making clinical trials more accessible and less burdensome.
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