三篇背靠背《Cell》，都離不開Octet®...

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1. Dual BACH1 regulation by complementary SCF-type E3 ligases.Cell,2024

2. Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus.Cell.2024

3. The WDR11 complex is a receptor for acidic-cluster-containing cargo proteins.Cell,2024

4. Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype.Cell,2024

5. Multimodal targeting chimeras enable integrated immunotherapy leveraging tumor-immune microenvironment.Cell.2024

6. TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.Cell.2024

7. A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification.Cell.2024

8. Preclinical proof of principle for orally delivered Th17 antagonist miniproteins.Cell.2024

9. Human coronavirus HKU1 recognition of the TMPRSS2 host receptor.Cell.2024

10. Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress.Cell.2024

11. A conserved fertilization complex bridges sperm and egg in vertebrates.Cell.2024

12. ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion.Cell.2024

13. Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies.Cell.2024

14. Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.Cell.2024

15. Vaccine induction of CD4-mimicking HIV-1 broadly neutralizing antibody precursors in macaques.Cell,2024

16. STK19 positions TFIIH for cell-free transcription-coupled DNA repair.Cell

17. IGSF8 is an innate immune checkpoint and cancer immunotherapy target.Cell,2024

18. Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.Cell,2024

19. Structure of apolipoprotein B100 bound to the low-density lipoprotein receptor.Nature,2024

20. Broadly inhibitory antibodies to severe malaria virulence proteins.Nature,2024

21. Design of customized coronavirus receptors.Nature,2024

22. Transferrin receptor targeting chimeras for membrane protein degradation.Nature, 2024

23. Designed endocytosis-inducing proteins degrade targets and amplify signals.Nature,2024

24. Shifts in receptors during submergence of an encephalitic arbovirus.Nature,2024

25. NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance.Nature,2024

26. Computational design of soluble and functional membrane protein analogues.Nature,2024

27. Selective haematological cancer eradication with preserved haematopoiesis.Nature,2024

28. Mechanism of single-stranded DNA annealing by RAD52–RPA complex.Nature,2024

29. HIV-1 capsids enter the FG phase of nuclear pores like a transport receptor.Nature,2024

30. Unsupervised evolution of protein and antibody complexes with a structure-informed language model.Science,2024

31. A neutralizing antibody prevents postfusion transition of measles virus fusion protein.Science,2024

32. Continuous evolution of compact protein degradation tags regulated by selective molecular glues.Science,2024

33. Hepatic glycogenesis antagonizes lipogenesis by blocking S1P via UDPG.Science,2024

34. Coupling antigens from multiple subtypes of influenza can broaden antibody and T cell responses.Science,2024