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BPS Bioscience Inc.
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當(dāng)前位置:BPS Bioscience Inc.>>Kinase>> 40326EGFR (T790M/C797S/ L858R) Kinase Assay Kit

EGFR (T790M/C797S/ L858R) Kinase Assay Kit

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產(chǎn)品型號40326

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更新時(shí)間:2024-01-31 18:05:02瀏覽次數(shù):144次

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●Purchase●DescriptionTheepidermalgrowthfactorreceptor(EGFR;ErbB-1;HER1)isthecellsurfacereceptorformembersoftheepidermalgrowthfactorfamily
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Description

The epidermal growth factor receptor (EGFR; ErbB-1; HER1) is the cellsurface receptor for members of the epidermal growth factor family. Overexpression and/or hyperactivation of EGFR kinase is associated with several human cancers such as lung, glioblastoma, and epithelian tumors of the neck and head, leading to the development of anticancer therapeutics targeting EGFR. T790M, L858R and C797S mutations in EGFR cause resistance to known EGFR inhibitors. The EGFR(T790M/C797S/L858R) Kinase Assay Kit is designed to identify mutant-selective EGFR kinase inhibitors and to measure EGFR (T790M/C797S/L858R) kinase activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.

Synonyms
EGFR, Epidermal Growth Factor Receptor, ERBB, ErbB-1, HER1, MENA

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