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Ochromycinone

CAS No. : 111540-00-2

產品活性：Ochromycinone ((Rac)-STA-21) is a natural antibiotic and a STAT3 inhibitor. Ochromycinone can inhibits STAT3 DNA binding activity, STAT3 dimerization. Ochromycinone has anticancer and antimicrobial activity.

研究領域：JAK/STAT Signaling  |  Stem Cell/Wnt  |  Anti-infection

作用靶點：STAT  |  Bacterial

結構分類：醌類  |  蒽醌類  |  酚類  |  單酚類

In Vitro: STA-21 inhibits STAT3 DNA binding activity, STAT3 dimerization, and STAT3-dependent luciferase activity. Moreover, STA-21 reduces the survival of breast carcinoma cells with constitutive STAT3 signaling but has minimal effect on the cells in which constitutive STAT3 signaling is absent.

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