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小鼠睪丸上皮細(xì)胞15P-1

種屬	小鼠
別稱(chēng)	15P-1
組織來(lái)源	睪丸
疾病	轉(zhuǎn)化細(xì)胞系
傳代比例/細(xì)胞消化	1:2傳代，消化2-3分鐘
培養(yǎng)基配置	DMEM養(yǎng)基；10%胎牛血清；1%雙抗
簡(jiǎn)介	15P-1細(xì)胞來(lái)源于在生精上皮中表達(dá)多瘤病毒(PyLT)大T蛋白的轉(zhuǎn)基因小鼠的睪丸細(xì)胞。該細(xì)胞表現(xiàn)出支持細(xì)胞 (Sertoli cells)的特征，包括轉(zhuǎn)錄威爾姆斯腫瘤(WT1)和Steel基因。據(jù)報(bào)道，15P-1培養(yǎng)物呈現(xiàn)出吞噬活性，乳膠顆粒的內(nèi)吞和死細(xì)胞的清除就證明了這個(gè)吞噬活性。與生殖細(xì)胞的相互作用增強(qiáng)了15P-1細(xì)胞的吞噬活性。與二倍體的減數(shù)分裂前期的生殖細(xì)胞共培養(yǎng)時(shí)，該細(xì)胞支持精原細(xì)胞經(jīng)減數(shù)分裂和減數(shù)分裂后分化成為表達(dá)(Prm- 1)基因的單倍體精子。
形態(tài)	上皮細(xì)胞樣
生長(zhǎng)特征	貼壁生長(zhǎng)
倍增時(shí)間	每周 2 至 3 次
保藏機(jī)構(gòu)	ATCC;CRL-2618

immune monitoring strategies will be examined herein, and genomic-based assays complementing these techniques will also be discussed. Finally, host genomic and external environmental factors influencing anti-tumor immune responses will be considered, including the role of the gut microbiome. Though optimal immune monitoring techniques are in evolution, great promise exists in recent advances that will help guide patient selection as far as type,development status of MYC-related therapies, including therapeutic strategies targeting MYC and combined MYC-based immunotherapy. These studies have reported extraordinary insights into the translational application of MYC in cancer treatment and are conducive to the emergence of