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CA VIII rabbit pAb
  • CA VIII rabbit pAb
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更新時間:2025-03-10 21:00:08

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SourceRabbitApplicationsIHC,ELISAReactivityHuman,Mouse,RatDilutionIHC:1:100-1:300
  • Source

    Rabbit

  • Applications

    IHC,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    CA VIII Polyclonal Antibody detects endogenous levels of CA VIII protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized peptide derived from the Internal region of human CA VIII.

  • Uniprot No

    P35219

  • Alternative names

    CA8; CALS; Carbonic anhydrase-related protein; CARP; Carbonic anhydrase VIII; CA-VIII

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    carbonic anhydrase 8(CA8) Homo sapiens The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provid

  • Other

    CA8, Carbonic anhydrase-related protein

  • Mol.Wt (Da)

    32973

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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