電壓門控鈉通道5α抗體

英文名稱 SCN5A/Nav1.5
中文名稱 電壓門控鈉通道5α抗體
別    名 Cardiac tetrodotoxin insensitive voltage dependent sodium channel alpha subunit; CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; PFHB1; Scn5a (gene name); Scn5a; SCN5A_HUMAN; Sodium channel protein cardiac muscle alpha subunit; Sodium channel protein cardiac muscle alpha-subunit; Sodium channel protein cardiac muscle subunit alpha; Sodium channel protein type 5 subunit alpha; Sodium channel protein type V alpha subunit; Sodium channel protein type V subunit alpha; SSS1; VF1; Voltage gated sodium channel alpha subunit Nav1.5; Voltage-gated sodium channel alpha subunit Nav1.5; Voltage-gated sodium channel subunit alpha Nav1.5.

說 明 書 0.2ml  
研究領域
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Zebrafish, Sheep, Chimpanzee, mpanzee,
產品應用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 227kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Nav1.5/SCN5A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na(+) channel isoform. This channel is responsible for the initial upstroke of the action potential.

Function:
This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na(+) channel isoform. This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels. xy-0179R    PSD95突觸后密度蛋白95抗體
xy-0561R    P-selectin/CD62pP選擇素抗體
xy-0748R    PTEN一種腫瘤抑制基因抗體（N端）
xy-1115R    AMPK alpha-1腺苷單磷酸活化蛋白激酶α1/AMPK α 1抗體
xy-0040R    protein C維生素K依賴的蛋白C重鏈抗體
xy-2692R    Plexin A1神經叢蛋白A1抗體
xy-3517R    PAK4p21激活激酶4抗體
xy-3314R    Phospho-PAK4(Ser474) + PAK5(Ser602) + PAK6(Ser560)磷酸化p21激活激酶4/5/6抗體
xy-3315R    Phospho-PAK1(Ser199 + Ser204) + PAK2 (Ser192 + Ser197)磷酸化p21激活激酶1/2抗體
xy-3316R    Phospho-PAK1 + PAK2 + PAK3 (T423 + T402 + T421)磷酸化p21激活激酶1/2抗體
xy-3317R    Phospho-PAK2 (Ser20)磷酸化p21激活激酶2抗體
xy-3532R    PLCG 2磷酯酶Cγ2抗體
xy-3318R    Phospho-PDGFRA(Tyr1018)磷酸化血小板源性生長因子受體-α抗體
xy-3319R    Phospho-PDGFRA(Tyr754)磷酸化血小板源性生長因子受體-α抗體
xy-1346R    P73 proteinP73腫瘤抑制基因抗體
xy-4958R    PCGF1表觀抑制因子Polycomb家族成員PCGFl蛋白抗體
xy-12070R    P2Y10G蛋白偶聯嘌呤受體p2y10抗體
xy-0190R    PACAP-27/38腺苷酸環化酶激活肽-27/38抗體
xy-0534R    p19ARFp19ARF抑癌基因抗體
xy-0741R    CDKN1Ap21蛋白抗體
xy-1204R    P2Y1P2Y1受體抗體/嘌呤受體抗體
xy-0427R    P311 protein神經再生相關蛋白抗體
xy-0637R    P38 MAPK絲裂原活化蛋白激酶p38α抗體
xy-1069R    proCNP促尿鈉排泄肽前體C抗體
xy-0739R    PAP2c磷脂酸磷酸酶2C抗體
xy-1199R    PAX1配對盒基因1抗體
xy-1187R    PAX2配對盒基因2抗體
xy-3520R    PAK2p21激活激酶2抗體
xy-3534R    PLC beta 3磷酯酶Cβ3抗體
xy-3328R    Phospho-PEA15 (Ser104)磷酸化星形膠質細胞PEA15抗體
xy-3329R    Phospho-PEA15(Ser116)磷酸化星形膠質細胞PEA15抗體
xy-1712R    Pan Cytokeratin廣譜細胞角蛋白PCK抗體
xy-4550R    Pectinesterase果膠酶抗體
xy-9321R    PRPF4PRPF4蛋白抗體
xy-2036R    Penicillin G青霉素G抗體