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水溶Sulfo-Cyanine7.5 NHS ester
水溶Sulfo-Cyanine7.5 NHS ester
Sulfo-Cyanine7.5 is a near infrared water soluble and hydrophilic dye for the NIR imaging applications. The structure and spectra of the dye resemble indocyanine green (ICG) that has been approved for use in humans for years. However, unlike ICG, sulfo-Cyanine7.5 contains a trimethylene bridge that increases its quantum yield compared to ICG, and also has a linker arm for its attachment to proteins, peptides, and other molecules. This derivative is an NHS ester for the modification of amine groups.
General properties
| Appearance: | dark green solid |
| Mass spec M+ increment: | 950.2 |
| Molecular weight: | 1180.47 |
| Molecular formula: | C49H48N3K3O16S4 |
| Solubility: | good in water, DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
Spectral properties
| Excitation maximum, nm: | 778 |
| ε, L⋅mol−1⋅cm−1: | 222000 |
| Emission maximum, nm: | 797 |
| CF260: | 0.09 |
| CF280: | 0.09 |
