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南京科佰生物科技有限公司
主營產(chǎn)品： atcc代理,ATCC細胞系,ATCC細胞株,ATCC細胞庫購買 |
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聯(lián)系電話
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南京科佰生物科技有限公司
主營產(chǎn)品： atcc代理,ATCC細胞系,ATCC細胞株,ATCC細胞庫購買 |
聯(lián)系電話
| 參考價 | 面議 |
更新時間：2023-01-16 09:21:01瀏覽次數(shù)：537
聯(lián)系我們時請說明是化工儀器網(wǎng)上看到的信息，謝謝!
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 1ug |
|---|---|---|---|
| 貨號 | CBP10589 | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
CBP10589 | |
| Format | Genomic DNA |
| Description | MLH1, mutL homolog 1, is a tumor suppressor that dimerizes with Pms2 to form a component of the DNA mismatch repair (MMR) system, and is associated with microsatellite instability (MSI) and genomic stability. MLH1 promoter hypermethylation, resulting in Mlh1 deficiency, is frequently associated with sporadic colorectal, gastric, and esophageal cancers, and germline MLH1 mutations are associated with Lynch (Hereditary Nonpolyposis Colorectal Cancer) syndrome. |
| Technical Data | |
| DNA Change | c.462_463insT |
| AA Change | p.L155Sfs*17 |
| Mutation type | Frame_Shift_Ins |
| Zygosity | N/A |
| Allelic Frequency | N/A |
| Transcript | NM_000249.4 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr3-37050314--T |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4°C |
| Expiry | 36 months from the date of manufacture |
